Anti-CathepsinD Polyclonal Antibody
品牌：solarbio | 货号：K106506P
| 英文名称 | Anti-CathepsinD Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CTSD;CLN10;CPSD;HEL-S-130P; |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 60kDa |
| Gene ID | 1509 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CathepsinD |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CathepsinD |
| Subcellular Locations | Lysosome Secreted |
| Swiss Prot | P07339 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro enzyme. Activation involves the proteolytic removal of the 43 amino acid profragment and an internal cleavage to generate the two-chain form made up of 34 and 14 kDa subunits. Cathepsin D contains the mannose-6-phosphate lysosomal localization signal that targets the enzyme to the lysosomal compartment where it functions in the normal degradation of proteins. |