Anti-CD45 Polyclonal Antibody
品牌:solarbio | 货号:K106422P
| 英文名称 | Anti-CD45 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PTPRC;L-CA;T200;CD45R;GP180;LY5;B220 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 147kDa |
| Gene ID | 5788 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CD45 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CD45 |
| Subcellular Locations | Cell membrane |
| Swiss Prot | P08575 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). |