Anti-CD45 Polyclonal Antibody
品牌:solarbio | 货号:K106422P
英文名称 |
Anti-CD45 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PTPRC;L-CA;T200;CD45R;GP180;LY5;B220 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
147kDa |
Gene ID |
5788 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CD45 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CD45 |
Subcellular Locations |
Cell membrane |
Swiss Prot |
P08575 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). |