Anti-CD45 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD45 Polyclonal Antibody

品牌:solarbio | 货号:K106422P

英文名称 Anti-CD45 Polyclonal Antibody
宿主 Rabbit
别名 PTPRC;L-CA;T200;CD45R;GP180;LY5;B220
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 147kDa
Gene ID 5788
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD45
性状 液体
Public Immunogen Range A synthetic peptide of human CD45
Subcellular Locations Cell membrane
Swiss Prot P08575
克隆类型 Polyclonal Antibody
背景资料 Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).