Anti-BAIAP2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-BAIAP2 Polyclonal Antibody

品牌:solarbio | 货号:K008178P

英文名称 Anti-BAIAP2 Polyclonal Antibody
宿主 Rabbit
别名 BAP2;FLAF3;IRSP53
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 61kDa
Gene ID 10458
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human BAIAP2
性状 液体
Public Immunogen Range Recombinant protein of human BAIAP2
Subcellular Locations Cytoplasm Membrane
Swiss Prot Q9UQB8
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.