Anti-BAIAP2 Polyclonal Antibody
品牌:solarbio | 货号:K008178P
英文名称 |
Anti-BAIAP2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BAP2;FLAF3;IRSP53 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
61kDa |
Gene ID |
10458 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human BAIAP2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human BAIAP2 |
Subcellular Locations |
Cytoplasm Membrane |
Swiss Prot |
Q9UQB8 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |