Anti-IL10RA Polyclonal Antibody
品牌：solarbio | 货号：K008090P
| 英文名称 | Anti-IL10RA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD210;IL10R;CD210a;CDW210A;HIL-10R;IL-10R1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 63kDa |
| Gene ID | 3587 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IL10RA |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IL10RA |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | Q13651 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. |