Anti-AFP Polyclonal Antibody
品牌:solarbio | 货号:K008067P
| 英文名称 | Anti-AFP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AFPD;FETA;HPAFP |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 69kDa |
| Gene ID | 174 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AFP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AFP |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P02771 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |