Anti-GRIK2 Polyclonal Antibody
品牌:solarbio | 货号:K008053P
英文名称 |
Anti-GRIK2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EAA4;GLR6;MRT6;GLUK6;GLUR6;GluK2 |
应用 |
IHC |
稀释比例 |
IHC 1:30-150. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
102/98/66/94/77kDa |
Gene ID |
2898 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human GRIK2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human GRIK2 |
Subcellular Locations |
Membrane |
Swiss Prot |
Q13002 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. |