Anti-ADAMTS5 Polyclonal Antibody
品牌:solarbio | 货号:K007385P
英文名称 |
Anti-ADAMTS5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ADMP-2;ADAM-TS5;ADAMTS-5;ADAMTS11;ADAM-TS 5;ADAMTS-11;ADAM-TS 11 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
102kDa |
Gene ID |
11096 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ADAMTS5 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ADAMTS5 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q9UNA0 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. |