Anti-RAB6A Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-RAB6A Polyclonal Antibody

品牌:solarbio | 货号:K007382P

英文名称 Anti-RAB6A Polyclonal Antibody
宿主 Rabbit
别名 RAB6
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 24kDa
Gene ID 5870
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human RAB6A
性状 液体
Public Immunogen Range A synthetic peptide of human RAB6A
Subcellular Locations Cytoplasm
Swiss Prot P20340
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.