Anti-CREBZF Polyclonal Antibody
品牌：solarbio | 货号：K007363P
| 英文名称 | Anti-CREBZF Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ZF;SMILE |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 37kDa |
| Gene ID | 58487 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CREBZF |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CREBZF |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9NS37 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Host cell factor (HCF) is a cellular cofactor required for the activation of VP16 which expresses the herpes simplex virus immediate early gene. V16 binds to HCF through a 4-amino acid motif similar to the HCF binding domain of the basic leucine-zipper proteins Luman and Zhangfei (ZF). Luman activates promoters containing cAMP or unfolded protein response elements (UPRE). Zhangfei suppresses the transcriptional activity of Luman, but requires HCF binding which may target Luman and Zhangfei to a common location. Sequence analysis predicts that the deduced 272-amino acid Zhangfei protein has a negatively charged N terminus, a leucine zipper of 6 heptad leucine repeats separated by a conserved 6-amino acid spacer, a basic domain, and a bZIP region. It is also presumed that the N-terminal acidic region of Zhangfei is an activation domain. |