Anti-WFS1 Polyclonal Antibody
品牌：solarbio | 货号：K007261P
| 英文名称 | Anti-WFS1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | WFS;WFRS;WFSL;CTRCT41 |
| 应用 | IHC |
| 稀释比例 | IHC 1:20-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 100kDa |
| Gene ID | 7466 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human WFS1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human WFS1 |
| Subcellular Locations | Cell membrane |
| Swiss Prot | O76024 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene. |