Anti-CARD8 Polyclonal Antibody
品牌：solarbio | 货号：K006973P
| 英文名称 | Anti-CARD8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NDPP;DACAR;DAKAR;NDPP1;TUCAN;CARDINAL |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 49kDa |
| Gene ID | 22900 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CARD8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CARD8 |
| Subcellular Locations | Nucleus Cytoplasm |
| Swiss Prot | Q9Y2G2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. |