Anti-ALKBH1 Polyclonal Antibody
品牌：solarbio | 货号：K006862P
| 英文名称 | Anti-ALKBH1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ABH;ABH1;alkB;hABH;ALKBH |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 44kDa |
| Gene ID | 8846 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ALKBH1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ALKBH1 |
| Subcellular Locations | Mitochondrion Nucleus |
| Swiss Prot | Q13686 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. |