Anti-AADAC Polyclonal Antibody
品牌：solarbio | 货号：K006859P
| 英文名称 | Anti-AADAC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DAC;CES5A1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 46kDa |
| Gene ID | 13 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AADAC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AADAC |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P22760 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores. |