Anti-Phospho-MAP2K4-S257/T261 Polyclonal Antibody
品牌：solarbio | 货号：K006234P
| 英文名称 | Anti-Phospho-MAP2K4-S257/T261 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | JNKK;JNKK1;MAPKK4;MEK4;MKK4;PRKMK4;SAPKK-1;SAPKK1;SEK1;SERK1;SKK1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 44kDa |
| Gene ID | 6416 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding S257/T261 of human MAP2K4 |
| 性状 | 液体 |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding S257/T261 of human MAP2K4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P45985 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. |