Anti-Phospho-RELA-S311 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-RELA-S311 Polyclonal Antibody

品牌:solarbio | 货号:K006216P

英文名称 Anti-Phospho-RELA-S311 Polyclonal Antibody
宿主 Rabbit
别名 NFKB3;p65
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human
蛋白分子量 60kDa
Gene ID 5970
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding S311 of human RELA
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding S311 of human RELA
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q04206
克隆类型 Polyclonal Antibody
背景资料 NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.