Anti-DSG3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-DSG3 Polyclonal Antibody

品牌:solarbio | 货号:K005817P

英文名称 Anti-DSG3 Polyclonal Antibody
宿主 Rabbit
别名 CDHF6;PVA
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 108kDa
Gene ID 1830
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human DSG3
性状 液体
Public Immunogen Range Recombinant protein of human DSG3
Subcellular Locations Cell junction Cell membrane Single-pass type I membrane protein desmosome
Swiss Prot P32926
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.