Anti-NDUFA1 Polyclonal Antibody
品牌：solarbio | 货号：K005759P
| 英文名称 | Anti-NDUFA1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CI-MWFE;MWFE;ZNF183 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 8kDa |
| Gene ID | 4694 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NDUFA1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NDUFA1 |
| Subcellular Locations | Mitochondrion |
| Swiss Prot | O15239 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the “hydrophobic protein” (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. |