Anti-CHRFAM7A Polyclonal Antibody
品牌：solarbio | 货号：K005499P
| 英文名称 | Anti-CHRFAM7A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CHRNA7;CHRNA7-DR1;D-10 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 46kDa |
| Gene ID | 89832 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CHRFAM7A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CHRFAM7A |
| Subcellular Locations | Membrane Multi-pass membrane protein |
| Swiss Prot | Q494W8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. |