Anti-NBN Polyclonal Antibody
品牌：solarbio | 货号：K005401P
| 英文名称 | Anti-NBN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AT-V1;AT-V2;ATV;NBS;NBS1;P95 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 85kDa |
| Gene ID | 4683 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NBN |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NBN |
| Subcellular Locations | Chromosome Nucleus PML body telomere |
| Swiss Prot | O60934 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |