Anti-LOX Polyclonal Antibody
品牌:solarbio | 货号:K005397P
英文名称 |
Anti-LOX Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
AAT10 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
47kDa |
Gene ID |
4015 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human LOX |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human LOX |
Subcellular Locations |
Secreted extracellular space |
Swiss Prot |
P28300 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. |