Anti-TNFRSF8 Polyclonal Antibody
品牌:solarbio | 货号:K005370P
| 英文名称 | Anti-TNFRSF8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD30;D1S166E;Ki-1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 64kDa |
| Gene ID | 943 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human TNFRSF8 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human TNFRSF8 |
| Subcellular Locations | Cell membrane Cytoplasm Single-pass type I membrane protein |
| Swiss Prot | P28908 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |