Anti-ALDOB Polyclonal Antibody
品牌：solarbio | 货号：K003688P
| 英文名称 | Anti-ALDOB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ALDB;ALDO2 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 39kDa |
| Gene ID | 229 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ALDOB |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ALDOB |
| Subcellular Locations | Cytoplasm centriolar satellite centrosome cytoskeleton microtubule organizing center |
| Swiss Prot | P05062 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related ‘housekeeping’ genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. |