Anti-ITGA6 Polyclonal Antibody
品牌:solarbio | 货号:K003638P
英文名称 |
Anti-ITGA6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD49f;ITGA6B;VLA-6 |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
127kDa |
Gene ID |
3655 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ITGA6 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ITGA6 |
Subcellular Locations |
Cell membrane Lipid-anchor Single-pass type I membrane protein |
Swiss Prot |
P23229 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. |