Anti-BAIAP2 Polyclonal Antibody
品牌：solarbio | 货号：K003920P
| 英文名称 | Anti-BAIAP2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BAP2;FLAF3;IRSP53 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 61kDa |
| Gene ID | 10458 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BAIAP2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BAIAP2 |
| Subcellular Locations | Cell projection Cytoplasm Membrane Peripheral membrane protein cytoskeleton filopodium ruffle |
| Swiss Prot | Q9UQB8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |