Anti-SCP2 Polyclonal Antibody
品牌：solarbio | 货号：K003958P
| 英文名称 | Anti-SCP2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NLTP;NSL-TP;SCP-2;SCP-CHI;SCP-X;SCPX |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 59kDa |
| Gene ID | 6342 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SCP2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SCP2 |
| Subcellular Locations | Cytoplasm Mitochondrion Mitochondrion Peroxisome |
| Swiss Prot | P22307 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. |