Anti-LITAF Polyclonal Antibody
品牌：solarbio | 货号：K004017P
| 英文名称 | Anti-LITAF Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PIG7;SIMPLE;TP53I7 |
| 应用 | WB IHC IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IP 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 17kDa |
| Gene ID | 9516 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human LITAF |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human LITAF |
| Subcellular Locations | Cytoplasmic side Lysosome membrane Peripheral membrane protein |
| Swiss Prot | Q99732 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget’s disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. |