Anti-SKP1 Polyclonal Antibody
品牌：solarbio | 货号：K003423P
| 英文名称 | Anti-SKP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EMC19;OCP-II;OCP2;SKP1A;TCEB1L;p19A |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 19kDa |
| Gene ID | 6500 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SKP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SKP1 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | P63208 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. |