Anti-HAX1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HAX1 Polyclonal Antibody

品牌:solarbio | 货号:K004055P

英文名称 Anti-HAX1 Polyclonal Antibody
宿主 Rabbit
别名 HCLSBP1;HS1BP1;SCN3
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:10-100.
交叉反应 Human Mouse
蛋白分子量 32kDa
Gene ID 10456
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human HAX1
性状 液体
Public Immunogen Range Recombinant protein of human HAX1
Subcellular Locations Cytoplasmic vesicle Endoplasmic reticulum Mitochondrion Nucleus membrane Sarcoplasmic reticulum
Swiss Prot O00165
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.