Anti-HAX1 Polyclonal Antibody
品牌:solarbio | 货号:K004055P
英文名称 |
Anti-HAX1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HCLSBP1;HS1BP1;SCN3 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
32kDa |
Gene ID |
10456 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human HAX1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human HAX1 |
Subcellular Locations |
Cytoplasmic vesicle Endoplasmic reticulum Mitochondrion Nucleus membrane Sarcoplasmic reticulum |
Swiss Prot |
O00165 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. |