Anti-HLA-E Polyclonal Antibody
品牌：solarbio | 货号：K005831P
| 英文名称 | Anti-HLA-E Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HLA-6.2;QA1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 3133 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human HLA-E |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human HLA-E |
| Subcellular Locations | Membrane Single-pass type I membrane protein |
| Swiss Prot | P13747 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |