Anti-MCAM Polyclonal Antibody
品牌：solarbio | 货号：K007604P
| 英文名称 | Anti-MCAM Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD146;MUC18;HEMCAM;METCAM;MelCAM |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:40-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 72kDa |
| Gene ID | 4162 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MCAM |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MCAM |
| Subcellular Locations | Membrane |
| Swiss Prot | P43121 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |