Anti-PTPRA Polyclonal Antibody
品牌:solarbio | 货号:K007152P
英文名称 |
Anti-PTPRA Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LRP;HLPR;PTPA;HEPTP;HPTPA;RPTPA;PTPRL2;HPTPalpha;R-PTP-alpha |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
91kDa |
Gene ID |
5786 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PTPRA |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PTPRA |
Subcellular Locations |
Membrane |
Swiss Prot |
P18433 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. |