Anti-GLP1R Polyclonal Antibody
品牌：solarbio | 货号：K005907P
| 英文名称 | Anti-GLP1R Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GLP-1;GLP-1-R;GLP-1R |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Mouse Rat |
| 蛋白分子量 | 53kDa |
| Gene ID | 2740 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GLP1R |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human GLP1R |
| Subcellular Locations | Cell membrane Multi-pass membrane protein |
| Swiss Prot | P43220 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. |