Anti-CDK8 Polyclonal Antibody
品牌：solarbio | 货号：K004053P
| 英文名称 | Anti-CDK8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | K35 |
| 应用 | WB IP |
| 稀释比例 | WB 1:500-2000. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 53kDa |
| Gene ID | 1024 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CDK8 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CDK8 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P49336 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. |