Anti-NTRK1 Polyclonal Antibody
品牌:solarbio | 货号:K007565P
英文名称 |
Anti-NTRK1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MTC;TRK;TRK1;TRKA;Trk-A;p140-TrkA |
应用 |
IHC |
稀释比例 |
IHC 1:100-300. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
87/84/77kDa |
Gene ID |
4914 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human NTRK1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human NTRK1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P04629 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |