Anti-ATP2B2 Polyclonal Antibody
品牌：solarbio | 货号：K004834P
| 英文名称 | Anti-ATP2B2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PMCA2;PMCA2a;PMCA2i |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 137kDa |
| Gene ID | 491 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ATP2B2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ATP2B2 |
| Subcellular Locations | Cell junction Cell membrane Multi-pass membrane protein synapse |
| Swiss Prot | Q01814 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. |