Anti-PPL Polyclonal Antibody
品牌:solarbio | 货号:K004888P
英文名称 |
Anti-PPL Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PPL |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
205kDa |
Gene ID |
5493 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PPL |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PPL |
Subcellular Locations |
Cell junction Cell membrane Cytoplasm Mitochondrion Nucleus cytoskeleton desmosome |
Swiss Prot |
O60437 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. |