Anti-MANF Polyclonal Antibody
品牌：solarbio | 货号：K004932P
| 英文名称 | Anti-MANF Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARMET;ARP |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 21kDa |
| Gene ID | 7873 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MANF |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MANF |
| Subcellular Locations | Secreted |
| Swiss Prot | P55145 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. |