Anti-PTPRN Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PTPRN Polyclonal Antibody

品牌:solarbio | 货号:K004496P

英文名称 Anti-PTPRN Polyclonal Antibody
宿主 Rabbit
别名 IA-2;IA-2/PTP;IA2;ICA512;R-PTP-N
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 106kDa
Gene ID 5798
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PTPRN
性状 液体
Public Immunogen Range Recombinant protein of human PTPRN
Subcellular Locations Cell junction Cell membrane Cell projection Cytoplasmic vesicle Endosome Membrane Perikaryon Single-pass type I membrane protein axon secretory vesicle membrane synapse
Swiss Prot Q16849
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.