Anti-PTPRN Polyclonal Antibody
品牌:solarbio | 货号:K004496P
英文名称 |
Anti-PTPRN Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
IA-2;IA-2/PTP;IA2;ICA512;R-PTP-N |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
106kDa |
Gene ID |
5798 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PTPRN |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PTPRN |
Subcellular Locations |
Cell junction Cell membrane Cell projection Cytoplasmic vesicle Endosome Membrane Perikaryon Single-pass type I membrane protein axon secretory vesicle membrane synapse |
Swiss Prot |
Q16849 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants. |