Anti-PER1 Polyclonal Antibody
品牌：solarbio | 货号：K005847P
| 英文名称 | Anti-PER1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PER;RIGUI;hPER |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 136kDa |
| Gene ID | 5187 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PER1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PER1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | O15534 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. |