Anti-IL18BP Polyclonal Antibody
品牌：solarbio | 货号：K004534P
| 英文名称 | Anti-IL18BP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IL18BPa |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 21kDa |
| Gene ID | 10068 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IL18BP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IL18BP |
| Subcellular Locations | Secreted |
| Swiss Prot | O95998 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn’s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |