Anti-CTSB Polyclonal Antibody
品牌：solarbio | 货号：K006690P
| 英文名称 | Anti-CTSB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APPS;CPSB |
| 应用 | IHC |
| 稀释比例 | IHC 1:150-500. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 38kDa |
| Gene ID | 1508 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CTSB |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CTSB |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P07858 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. |