Anti-IL15RA Polyclonal Antibody
品牌：solarbio | 货号：K007516P
| 英文名称 | Anti-IL15RA Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD215 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 28kDa |
| Gene ID | 3601 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IL15RA |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IL15RA |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q13261 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. |