Anti-IL2RA Polyclonal Antibody
品牌:solarbio | 货号:K007517P
英文名称 |
Anti-IL2RA Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CD25;IL2R;TCGFR;IDDM10 |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
31kDa |
Gene ID |
3559 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human IL2RA |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human IL2RA |
Swiss Prot |
P01589 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |