Anti-IL2RA Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-IL2RA Polyclonal Antibody

品牌:solarbio | 货号:K007517P

英文名称 Anti-IL2RA Polyclonal Antibody
宿主 Rabbit
别名 CD25;IL2R;TCGFR;IDDM10
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量 31kDa
Gene ID 3559
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human IL2RA
性状 液体
Public Immunogen Range A synthetic peptide of human IL2RA
Swiss Prot P01589
克隆类型 Polyclonal Antibody
背景资料 The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.