Anti-GHRH Polyclonal Antibody
品牌:solarbio | 货号:K003924P
英文名称 |
Anti-GHRH Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
GHRF;GRF;INN |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
12kDa |
Gene ID |
2691 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human GHRH |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human GHRH |
Subcellular Locations |
Secreted |
Swiss Prot |
P01286 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |