Anti-DHCR24 Polyclonal Antibody
品牌：solarbio | 货号：K003971P
| 英文名称 | Anti-DHCR24 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DCE;Nbla03646;SELADIN1;seladin-1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 60kDa |
| Gene ID | 1718 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DHCR24 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DHCR24 |
| Subcellular Locations | Endoplasmic reticulum membrane Golgi apparatus membrane Single-pass membrane protein |
| Swiss Prot | Q15392 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. |