Anti-SLC17A1 Polyclonal Antibody
品牌：solarbio | 货号：K007845P
| 英文名称 | Anti-SLC17A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NPT1;NPT-1;NAPI-1 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human |
| 蛋白分子量 | 51kDa |
| Gene ID | 6568 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SLC17A1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SLC17A1 |
| Swiss Prot | Q14916 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1? and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport. |