Anti-CYP3A5 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CYP3A5 Polyclonal Antibody

品牌:solarbio | 货号:K007917P

英文名称 Anti-CYP3A5 Polyclonal Antibody
宿主 Rabbit
别名 CP35;PCN3;CYPIIIA5;P450PCN3
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human
蛋白分子量 57kDa
Gene ID 1577
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CYP3A5
性状 液体
Public Immunogen Range A synthetic peptide of human CYP3A5
Subcellular Locations Membrane
Swiss Prot P20815
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.?