Anti-CYP3A5 Polyclonal Antibody
品牌:solarbio | 货号:K007917P
英文名称 |
Anti-CYP3A5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CP35;PCN3;CYPIIIA5;P450PCN3 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human |
蛋白分子量 |
57kDa |
Gene ID |
1577 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CYP3A5 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CYP3A5 |
Subcellular Locations |
Membrane |
Swiss Prot |
P20815 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.? |