Anti-IGF1R Polyclonal Antibody
品牌：solarbio | 货号：K007958P
| 英文名称 | Anti-IGF1R Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | IGFR;CD221;IGFIR;JTK13 |
| 应用 | IHC |
| 稀释比例 | IHC 1:20-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 155kDa |
| Gene ID | 3480 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IGF1R |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IGF1R |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P08069 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.? |