Anti-ADSL Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ADSL Polyclonal Antibody

品牌:solarbio | 货号:K004403P

英文名称 Anti-ADSL Polyclonal Antibody
宿主 Rabbit
别名 AMPS;ASASE;ASL
应用 WB IF IP
稀释比例 WB 1:500-2000. IF 1:20-100. IP 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 55kDa
Gene ID 158
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ADSL
性状 液体
Public Immunogen Range Recombinant protein of human ADSL
Subcellular Locations Cytosol
Swiss Prot P30566
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.