Anti-XRCC5 Polyclonal Antibody
品牌：solarbio | 货号：K004266P
| 英文名称 | Anti-XRCC5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | KARP-1;KARP1;KU80;KUB2;Ku86;NFIV |
| 应用 | WB IHC IF IP |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. IF 1:20-100. IP 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 83kDa |
| Gene ID | 7520 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human XRCC5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human XRCC5 |
| Subcellular Locations | Chromosome Nucleus nucleolus |
| Swiss Prot | P13010 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |